| pos. | Title | Gross | |
|---|---|---|---|
| 1 | ![]() | Avengers: Infinity War (2018) | $1,822,705,498 |
| 2 | ![]() | Black Panther (2018) | $1,305,473,609 |
| 3 | ![]() | Jurassic World: Fallen Kingdom (2018) | $1,220,349,973 |
| 4 | ![]() | Incredibles 2 (2018) | $1,177,197,443 |
| 5 | ![]() | Venom (2018) | $855,085,151 |
| 6 | ![]() | Mission:Impossible - Fallout (2018) | $791,115,104 |
| 7 | ![]() | Aquaman (2018) | $748,785,000 |
| 8 | ![]() | Deadpool 2 (2018) | $745,045,464 |
| 9 | ![]() | Ant-Man and the Wasp (2018) | $615,610,605 |
| 10 | ![]() | Ready Player One (2018) | $537,832,402 |
| 11 | ![]() | The Meg (2018) | $530,243,742 |
| 12 | ![]() | The Nun (2018) | $365,550,119 |
| 13 | ![]() | A Star Is Born (2018) | $326,144,638 |
| 14 | ![]() | Ralph Breaks the Internet: Wreck-It Ralph 2 (2018) | $321,613,583 |
| 15 | ![]() | A Quiet Place (2018) | $313,142,143 |
| 16 | ![]() | The Grinch (2018) | $291,501,485 |
| 17 | ![]() | Fantastic Beasts: The Crimes of Grindelwald (2018) | $285,085,475 |
| 18 | ![]() | Bohemian Rhapsody (2018) | $282,143,523 |
| 19 | ![]() | Spider-Man: Into the Spider-Verse (2018) | $213,243,730 |
| 20 | ![]() | Crazy Rich Asians (2018) | $200,058,004 |