| pos. | Title | Gross | |
|---|---|---|---|
| 1 |  | Avatar (2009) | £74,203,082 |
| 2 |  | Toy Story 3 (2010) | £73,405,113 |
| 3 |  | Harry Potter and the Deathly Hallows Part 1 (2010) | £48,914,777 |
| 4 |  | Alice In Wonderland (2010) | £42,169,542 |
| 5 |  | Inception (2010) | £35,264,403 |
| 6 |  | Shrek Forever After (2010) | £31,106,087 |
| 7 |  | The Twilight Saga: Eclipse (2010) | £29,308,657 |
| 8 |  | Sherlock Holmes (2009) | £22,637,278 |
| 9 |  | Sex and the City 2 (2010) | £21,606,766 |
| 10 |  | Iron Man 2 (2010) | £20,923,193 |
| 11 |  | Clash of the Titans (2010) | £20,111,003 |
| 12 |  | Despicable Me (2010) | £19,692,265 |
| 13 |  | Alvin and the Chipmunks: The Squeakquel (2009) | £18,144,891 |
| 14 |  | How to Train Your Dragon (2010) | £16,858,382 |
| 15 |  | Nanny Mcphee and the Big Bang (2010) | £16,524,872 |
| 16 |  | Robin Hood (2010) | £15,440,353 |
| 17 |  | StreetDance 3D (2010) | £11,617,687 |
| 18 |  | The Karate Kid (2010) | £11,613,244 |
| 19 |  | Kick-Ass (2010) | £11,601,334 |
| 20 |  | The Chronicles of Narnia: The Voyage of the Dawn Treader (2010) | £11,263,418 |